Mark S. Rea, as Professor of Architecture and Cognitive Sciences at Rensselaer Polytechnic Institute, and now as a professor at the Icahn School of Medicine at Mount Sinai, I have been involved in modeling the human visual response to light, including a model of suprathreshold visual performance and of mesopic vision. My research team published the first models of both murine and human circadian phototransduction with application to Alzheimer’s disease research. I led the development of analytical techniques to quantify circadian disruption from rest/activity and light/dark patterns in humans that can be applied to animal models. I served as the Director of the Lighting Research Center at Rensselaer from 1988 to 2017 and have experience overseeing budgets, staff, and communications with sponsoring agencies such as the NIH. I have published more than 250 scientific and technical articles related to circadian rhythms, vision, human factors, lighting technologies, and applications. I was the editor-in-chief of the 8th and 9th editions of the Illuminating Engineering Society Lighting Handbook, the primary technical reference for the lighting industry.